Pulmoner arteriyel hipertansiyonlu hastalarda vagal-nöroimmünomodülasyon endeksinin rolü

Aim: The vagal neuroimmunomodulation (NIM) index is reflective of the cholinergic inflammatory tone in many clinical circumstances as well healthy individuals. We aimed to investigate relationship NIM-index on course patients with PAH.
 Material and Method: A total 31 diagnosed pulmonary arterial hypertension (PAH) were included this study. Data electrocardiography (ECG) C-reactive protein (CRP) retrospectively obtained from patients’ electronic files retrospectively. NIM was calculated heart rate variability (HRV) CRP ratio (HRV/CRP). 
 Results: During follow-up, most required hospitalization at least once (21 vs. 10 patients). Consistent current literature expected, there a significant difference between groups BNP values (394 ng/L vs 55 ng/L, p=0.005). HRV, CRP, not found be groups. Conclusion: associated need for PAH.